Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy

• Main Authors: Chenglin Liang (Author), Ge Zhang (Author), Linlin Guo (Author), Xinyi Ding (Author), Heng Yang (Author), Hongling Zhang (Author), Zhenzhong Zhang (Author), Lin Hou (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Induction of tumor cell senescence has become a promising strategy for anti-tumor immunotherapy, but fibrotic matrix severely blocks senescence inducers penetration and immune cells infiltration. Herein, we designed a cancer-associated fibroblasts (CAFs) triggered structure-transformable nano-assemb...