Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy

• Váldodahkkit: Chenglin Liang (Dahkki), Ge Zhang (Dahkki), Linlin Guo (Dahkki), Xinyi Ding (Dahkki), Heng Yang (Dahkki), Hongling Zhang (Dahkki), Zhenzhong Zhang (Dahkki), Lin Hou (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2024-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Induction of tumor cell senescence has become a promising strategy for anti-tumor immunotherapy, but fibrotic matrix severely blocks senescence inducers penetration and immune cells infiltration. Herein, we designed a cancer-associated fibroblasts (CAFs) triggered structure-transformable nano-assemb...