L-Carnitine Mitigates Oxidative Stress and Disorganization of Cytoskeleton Intermediate Filaments in Cisplatin-Induced Hepato-Renal Toxicity in Rats

• Main Authors: Ashraf Elkomy (Author), Ehab Yahya Abdelhiee (Author), Sabreen Ezzat Fadl (Author), Mahmoud Abdelghaffar Emam (Author), Fatma Abdel-Monem Gad (Author), Adham Sallam (Author), Saud Alarifi (Author), Mohamed M. Abdel-Daim (Author), Mohamed Aboubakr (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin (CP) is one of the most active medications in cancer treatment and has some adverse effects such as hepatotoxicity and nephrotoxicity. The present research was planned to determine the protective effects of L-carnitine (LC) against CP-induced hepato-renal oxidative stress in rats, via inve...