Montelukast Nanocrystals for Transdermal Delivery with Improved Chemical Stability

• Main Authors: Sung Hyun Im (Author), Hoe Taek Jung (Author), Myoung Jin Ho (Author), Jeong Eun Lee (Author), Hyung Tae Kim (Author), Dong Yoon Kim (Author), Hyo Chun Lee (Author), Yong Seok Choi (Author), Myung Joo Kang (Author)
• Format: Book
• Published: MDPI AG, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A novel nanocrystal system of montelukast (MTK) was designed to improve the transdermal delivery, while ensuring chemical stability of the labile compound. MTK nanocrystal suspension was fabricated using acid-base neutralization and ultra-sonication technique and was characterized as follows: approx...