Impact of Cabozantinib Exposure on Proteinuria and Muscle Toxicity in Patients with Unresectable Hepatocellular Carcinoma

• Main Authors: Hironao Okubo (Author), Hitoshi Ando (Author), Yusuke Takasaki (Author), Eisuke Nakadera (Author), Yuka Fukuo (Author), Shuichiro Shiina (Author), Kenichi Ikejima (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This prospective study investigated the impact of cabozantinib exposure on proteinuria and muscle toxicity, in a cohort of 14 Japanese patients with unresectable hepatocellular carcinoma (uHCC). We measured the trough concentration of cabozantinib (C_trough) weekly for 6 weeks...