Antinociceptive effects of AGAP, a recombinant neurotoxic polypeptide: Possible involvement of the tetrodotoxin-resistant sodium channels in small dorsal root ganglia neurons

• Main Authors: Li Chunli (Author), Liu Xifang (Author), Li Guixia (Author), Ban Mengqi (Author), Chen Jianzhao (Author), Cui Yong (Author), Zhang Jinghai (Author), Wu Chunfu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antitumor-analgesic peptide（AGAP）is a novel recombinant polypeptide. The primary study showed that AGAP 1.0 mg/kg exhibited strong analgesic and antitumor effects. The tail vein administration of AGAP potently reduced pain behaviors in mice induced by intraplantar injection of formalin or intraperit...