Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs
MGH2.1 is a herpes simplex virus type 1 (HSV1) oncolytic virus that expresses two prodrug-activating transgenes: the cyclophosphamide (CPA)-activating cytochrome P4502B1 (CYP2B1) and the CPT11-activating secreted human intestinal carboxylesterase (shiCE). Toxicology and biodistribution of MGH2.1 in...
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Main Authors: | Kazue Kasai (Author), Hiroshi Nakashima (Author), Fang Liu (Author), Samantha Kerr (Author), Jiang Wang (Author), Mitch Phelps (Author), Philip M Potter (Author), William B Goins (Author), Soledad A Fernandez (Author), E Antonio Chiocca (Author) |
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Format: | Book |
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Elsevier,
2013-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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