The glucocorticoid RU24858 does not distinguish between transrepression and transactivation in primary human eosinophils

• Main Authors: Zhang Xianzhi (Author), Hasala Hannele (Author), Moilanen Eeva (Author), Janka-Junttila Mirkka (Author), Adcock Ian (Author), Kankaanranta Hannu (Author)
• Format: Book
• Published: BMC, 2006-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Glucocorticoids are used to treat chronic inflammatory diseases such as asthma. Induction of eosinophil apoptosis is considered to be one of the main mechanisms behind the anti-asthmatic effect of glucocorticoids. Glucocorticoid bind...