Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis

• Main Authors: Saima (Author), Irfan Anjum (Author), Aisha Mobashar (Author), Shah Jahan (Author), Saima Najm (Author), Hiba-Allah Nafidi (Author), Yousef A. Bin Jardan (Author), Mohammed Bourhia (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apigenin is a phytochemical obtained from <i>Chamomilla recutita.</i> Its role in interstitial cystitis is not yet known. The present study is aimed at understanding the uroprotective and spasmolytic effects of apigenin in cyclophosphamide-induced interstitial cystitis. The uroprotective...