Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration

• Main Authors: Aquib Ehtram (Author), Mohd Shariq (Author), Sabeeha Ali (Author), Neha Quadir (Author), Javaid A. Sheikh (Author), Faraz Ahmad (Author), Tarina Sharma (Author), Nasreen Z. Ehtesham (Author), Seyed E. Hasnain (Author)
• Format: Book
• Published: Elsevier, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M. tb) harbours one of the most rigid cell envelopes across bacterial genera and is devoid of...