Detection of antibiotic resistance in leprosy using GenoType LepraeDR, a novel ready-to-use molecular test.

• Main Authors: Emmanuelle Cambau (Author), Aurélie Chauffour-Nevejans (Author), Liana Tejmar-Kolar (Author), Masanori Matsuoka (Author), Vincent Jarlier (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Although leprosy is efficiently treated by multidrug therapy, resistance to first-line (dapsone, rifampin) and to second-line drugs (fluoroquinolones) was described worldwide. Since Mycobacterium leprae is not growing in vitro, phenotypic susceptibility testing requires a one year experi...