Kaposiform Lymphangiomatosis in a Male Adolescent: A Clinical Challenge and the Role of Genetics

• Main Authors: Joana Pereira-Nunes MD (Author), Miguel Madureira MD (Author), Alexandra Dinis MD (Author), Helena Barroca MD (Author), Jorge Lima Msc (Author), Maria do Bom-Sucesso MD (Author)
• Format: Book
• Published: SAGE Publishing, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Kaposiform lymphangiomatosis (KLA) is a rare and aggressive generalized lymphatic anomaly (GLA), with distinctive clinical, radiology, morphologic, and genetic features. It does not have a current standard treatment and presents poor overall prognosis. Somatic mutations in the RAS pathway were repor...