First pilot case-control interventional study using autologous extracellular vesicles to treat chronic venous ulcers unresponsive to conventional treatments

• Main Authors: Lorenzo Gibello (Author), Sergio D'Antico (Author), Marika Salafia (Author), Rebecca Senetta (Author), Margherita Alba Carlotta Pomatto (Author), Giulia Orlando (Author), Alessandro Sarcinella (Author), Tatiana Lopatina (Author), Pietro Quaglino (Author), Marco Lorenzi (Author), Fabio Verzini (Author), Giovanni Camussi (Author), Maria Felice Brizzi (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current therapeutic approaches for chronic venous ulcers (CVUs) still require evidence of effectiveness. Diverse sources of extracellular vesicles (EVs) have been proposed for tissue regeneration, however the lack of potency tests, to predict in-vivo effectiveness, and a reliable scalability have de...