A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in methyl-CpG-binding protein-2 (MECP2), a transcriptional regulator of many genes, including brain-derived neurotrophic factor (BDNF). BDNF levels are reduced in RTT autopsy brains and in multiple brain areas of Mecp2-deficien...

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Bibliographic Details
Main Authors: Wei Li (Author), Alba Bellot-Saez (Author), Mary L. Phillips (Author), Tao Yang (Author), Frank M. Longo (Author), Lucas Pozzo-Miller (Author)
Format: Book
Published: The Company of Biologists, 2017-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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