Genetically engineered nano‐melittin vesicles for multimodal synergetic cancer therapy

• Main Authors: Jianzhong Zhang (Author), Xue Liu (Author), Yutian Xia (Author), Shuyu Xu (Author), Xuan Liu (Author), Haiqing Xiao (Author), Xiaoyong Wang (Author), Chao Liu (Author), Gang Liu (Author)
• Format: Book
• Published: Wiley, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Melittin, the principal constituent in bee venom, is an attractive candidate for cancer therapy. However, its clinical applications are limited by hemolysis, nonspecific cytotoxicity, and rapid metabolism. Herein, a novel genetically engineered vesicular antibody‐melittin (VAM) drug deliver...