The acute lymphoblastic leukemia prognostic scoring whether it is possible by BCL-2, BAX gene promoter genotyping

• Main Authors: Mozhgan Moazami-Goudarzi (Author), Majid Farshdousti-Hagh (Author), Abbasali Hoseinpour-Feizi (Author), Mehdi Talebi (Author), Ali-Akbar Movassa (Author), Karim Shams-Asanjan (Author), Jamal Eyvazi-Ziyaee (Author), Morteza Seifi (Author)
• Format: Book
• Published: Babol University of Medical Sciences, 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: BCL-2 is the most important anti-apoptotic regulator and Bax is a pro-apoptotic protein. The status of these parameters or the ration of BCL-2 to BAX is important in malignant cell fate as well as normal cells. Methods: Sixty-two ALL patients and 62 healthy sex-and age-matched controls w...