In vivo and in vitro effects of crocetin and its amide derivative on acrylamide-induced neurotoxicity

• Main Authors: Amir Hossein Ajzashokouhi (Author), Bibi Marjan Razavi (Author), Hamid Sadeghian (Author), Hossein Hosseinzadeh (Author)
• Format: Book
• Published: Mashhad University of Medical Sciences, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Acrylamide (ACR) is a neurotoxic agent whose damage could be attenuated by antioxidants administration. Crocetin is a saffron-derived antioxidant that has neuroprotective effects. This study evaluates the protective effects of trans-sodium crocetinate (TSC) and its water-soluble derivativ...