Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy

• Ngā kaituhi matua: Lukas Amon (Author), Lukas Hatscher (Author), Lukas Heger (Author), Diana Dudziak (Author), Christian H. K. Lehmann (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2020-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The onset of checkpoint inhibition revolutionized the treatment of cancer. However, studies from the last decade suggested that the sole enhancement of T cell functionality might not suffice to fight malignancies in all individuals. Dendritic cells (DCs) are not only part of the innate immune system...