Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi.

• Main Authors: Adriana Egui (Author), Paola Lasso (Author), María Carmen Thomas (Author), Bartolomé Carrilero (Author), John Mario González (Author), Adriana Cuéllar (Author), Manuel Segovia (Author), Concepción Judith Puerta (Author), Manuel Carlos López (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital T. cruzi infections involve multiple factors in which complex interactions between the parasite and the immune system of pregnant women play important roles. In this study, we used an experimental murine model of chronic infection with T. cruzi to evaluate the changes in the expression of...