CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors

A human single-chain variable fragment (scFv) antibody library was expressed on the surface of human T cells after transduction with lentiviral vectors (LVs). The repertoire was fused to a first-generation T cell receptor ζ (TCRζ)-based chimeric antigen receptor (CAR). We used this library to isolat...

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Main Authors: Vanesa Alonso-Camino (Author), David Sánchez-Martín (Author), Marta Compte (Author), Natalia Nuñez-Prado (Author), Rosa M Diaz (Author), Richard Vile (Author), Luis Alvarez-Vallina (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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Call Number: A1234.567
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