Strategies and Applications of Antigen-Binding Fragment (Fab) Production in Escherichia coli

• Main Authors: Hui Chen (Author), Jun-Sheng Chen (Author), Pameila Paerhati (Author), Tanja Jakos (Author), Si-Yi Bai (Author), Jian-Wei Zhu (Author), Yun-Sheng Yuan (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

With the advancement of genetic engineering, monoclonal antibodies (mAbs) have made far-reaching progress in the treatment of various human diseases. However, due to the high cost of production, the increasing demands for antibody-based therapies have not been fully met. Currently, mAb-derived alter...