Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells

• Main Authors: Loredana Salerno (Author), Antonietta Notaro (Author), Valeria Consoli (Author), Federica Affranchi (Author), Valeria Pittalà (Author), Valeria Sorrenti (Author), Luca Vanella (Author), Michela Giuliano (Author), Sebastiano Intagliata (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractColon cancer remains a clinical challenge in industrialised countries. Its treatment with 5-Flurouracil (5-FU) develops many side effects and resistance. Thus, several strategies have been undertaken so far, including the use of drug cocktails and polypharmacology. Heme oxygenase-1 (HO-1) is...