Formyl Peptide Receptor 1 and 2 Dual Agonist Inhibits Human Neutrophil Chemotaxis by the Induction of Chemoattractant Receptor Cross-desensitization
Formyl peptide receptor 1 (FPR1) and FPR2/ALX are known to control neutrophil chemotaxis in response to various ligands. In this study, we investigated the inhibitory mechanism of compound 43 (Cpd43), an FPR1 and FPR2/ALX dual agonist, on human neutrophil chemotaxis. Precedent stimulation of human p...
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Main Authors: | Yoshitaka Sogawa (Author), Takao Ohyama (Author), Hiroaki Maeda (Author), Kazuki Hirahara (Author) |
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Format: | Book |
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Elsevier,
2011-01-01T00:00:00Z.
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