Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments

• Автори: Adam J. Rauckhorst (Автор), Nicholas Borcherding (Автор), Daniel J. Pape (Автор), Alora S. Kraus (Автор), Diego A. Scerbo (Автор), Eric B. Taylor (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2022-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Objective: Metabolomics as an approach to solve biological problems is exponentially increasing in use. Thus, this a pivotal time for the adoption of best practices. It is well known that disrupted tissue oxygen supply rapidly alters cellular energy charge. However, the speed and extent to which del...