Dopaminergic antagonists inhibit bile chemotaxis of adult Clonorchis sinensis and its egg production.

• Main Authors: Fuhong Dai (Author), Jin-Ho Song (Author), Yeon Pyo Hong (Author), Xuelian Bai (Author), Woon-Mok Sohn (Author), Sung-Jong Hong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human clonorchiasis, caused by Clonorchis sinensis, is endemic in East Asian countries. C. sinensis metacercariae excyst in the duodenum of mammalian hosts, migrate to the intrahepatic bile duct, and mature into adults in the milieu of bile. We have previously shown that newly excysted juvenile C. s...