Recent advances in the development of RIPK2 modulators for the treatment of inflammatory diseases

• Hoofdauteurs: Anh-Tuan Pham (Auteur), Amanda Franceschini Ghilardi (Auteur), Lijun Sun (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Receptor-interacting serine/threonine kinase 2 (RIPK2) is a vital immunomodulator that plays critical roles in nucleotide-binding oligomerization domain 1 (NOD1), NOD2, and Toll-like receptors (TLRs) signaling. Stimulated NOD1 and NOD2 interact with RIPK2 and lead to the activation of nuclear factor...