Inhibitory Effect of Lomerizine, a Prophylactic Drug for Migraines, on Serotonin-Induced Contraction of the Basilar Artery

• 主要な著者: Masakazu Ishii (著者), Shunsuke Kobayashi (著者), Masamichi Ohkura (著者), Ryuichi Yamamoto (著者), Shunichi Shimizu (著者), Yuji Kiuchi (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2009-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

We examined the effects of lomerizine on serotonin (5-hydroxytryptamine, 5-HT)- induced contraction of the basilar artery and compared them with those of nifedipine. Although both lomerizine and nifedipine completely blocked K+-induced vasoconstriction, 5-HT-induced vasoconstriction was more strongl...