Outcomes of Peptide Vaccine GV1001 Treatment in a Murine Model of Acute Noise-Induced Hearing Loss

• Principais autores: Sang-Yeon Lee (Autor), Jae Joon Han (Autor), Sang-Youp Lee (Autor), Gaon Jung (Autor), Hyun Jin Min (Autor), Jae-Jin Song (Autor), Ja-Won Koo (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Noise-induced hearing loss (NIHL) is primarily caused by damage to cochlear hair cells, associated with synaptopathy. The novel cell-penetrating peptide GV1001, an antitumor agent, also has antioxidant and anti-inflammatory effects, and is otoprotective in a murine model of kanamycin-induced ototoxi...