The use of cyclic peptide antigens to generate LRP8 specific antibodies

• Main Authors: Maria A. Argiriadi (Author), Kangwen Deng (Author), David Egan (Author), Lei Gao (Author), Farid Gizatullin (Author), John Harlan (Author), Denise Karaoglu Hanzatian (Author), Wei Qiu (Author), Ruth Villanueva (Author), Andrew Goodearl (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

LRP8 is a member of the LDLR-like protein family. It is a transport receptor, which can be used in the design of antibodies specific for investigating increasing exposure to therapeutics with respect to the blood brain barrier (BBB). In this study, a LRP8 peptide immunization strategy was implemente...