Glucocorticoids Ameliorate Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness by Inhibiting Upregulation of RhoA in Rats

• Главные авторы: Yoshihiko Chiba (Автор), Kumiko Goto (Автор), Mayu Hirahara (Автор), Hiroyasu Sakai (Автор), Miwa Misawa (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2008-01-01T00:00:00Z.
• Предметы: article
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To determine the mechanism(s) of the inhibitory effect of glucocorticoids on airway hyperresponsiveness in allergic bronchial asthma, the effects of systemic treatment with glucocorticoids on bronchial smooth muscle hyperresponsiveness and RhoA upregulation were investigated in rats with allergic br...