N-Substituted Pyrrole Derivative 12m Inhibits HIV-1 Entry by Targeting Gp41 of HIV-1 Envelope Glycoprotein

• Main Authors: Jiayin Qiu (Author), Taizhen Liang (Author), Junyan Wu (Author), Fei Yu (Author), Xiaoyang He (Author), Yuanxin Tian (Author), Lan Xie (Author), Shibo Jiang (Author), Shuwen Liu (Author), Lin Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The combination of three or more antiviral agents that act on different targets is known as highly active antiretroviral therapy (HAART), which is widely used to control HIV infection. However, because drug resistance and adverse effects occur after long-term administration, an increasing number of...