The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells

• Váldodahkkit: Juan Sebastian Yakisich (Dahkki), Neelam Azad (Dahkki), Vivek Kaushik (Dahkki), Anand K. V. Iyer (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2019-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The biguanides metformin (MET) and to a lesser extent buformin (BUF) have recently been shown to exert anticancer effects. In particular, MET targets cancer stem cells (CSCs) in a variety of cancer types but these compounds have not been extensively tested for combination therapy. In this study, we...