Cover Image

The mitochondrial pyruvate carrier regulates adipose glucose partitioning in female mice

Objective: The mitochondrial pyruvate carrier (MPC) occupies a critical node in intermediary metabolism, prompting interest in its utility as a therapeutic target for the treatment of obesity and cardiometabolic disease. Dysregulated nutrient metabolism in adipose tissue is a prominent feature of ob...

Full description

Saved in:

Bibliographic Details
Main Authors:	Christopher E. Shannon (Author), Terry Bakewell (Author), Marcel J. Fourcaudot (Author), Iriscilla Ayala (Author), Annie A. Smelter (Author), Edgar A. Hinostroza (Author), Giovanna Romero (Author), Mara Asmis (Author), Leandro C. Freitas Lima (Author), Martina Wallace (Author), Luke Norton (Author)
Format:	Book
Published:	Elsevier, 2024-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease
by: Chris E. Shannon, et al.
Published: (2021)

Recent Advances in Mitochondrial Pyruvate Carrier Inhibitors
by: Yilei Huang, et al.
Published: (2024)

An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion
by: Kyle S. McCommis, et al.
Published: (2016)

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
by: Sotiria Tavoulari, et al.
Published: (2022)

Partitive Determiners, Partitive Pronouns and Partitive Case
Published: (2021)

Partitive Determiners, Partitive Pronouns and Partitive Case
Published: (2021)

The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity
by: Adam J. Rauckhorst, et al.
Published: (2017)

Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian cancer
by: M. Rufaik Farook, et al.
Published: (2024)

Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury
by: Adam J. Rauckhorst, et al.
Published: (2024)

Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism
by: Daniel Ferguson, et al.
Published: (2023)

Reprogramming hormone-sensitive prostate cancer to a lethal neuroendocrine cancer lineage by mitochondrial pyruvate carrier (MPC)
by: Huan Xu, et al.
Published: (2022)

Glucose-1,6-bisphosphate: A new gatekeeper of cerebral mitochondrial pyruvate uptake
by: Motahareh Solina Safari, et al.
Published: (2024)

Inhibition of Pyruvate Dehydrogenase in the Heart as an Initiating Event in the Development of Diabetic Cardiomyopathy
by: Abdallah Elnwasany, et al.
Published: (2023)

Partition-Based Trapdoor Ciphers
Published: (2017)

Partitions and Atoms of Clause Structure
by: Sportiche, Dominique
Published: (1998)

Partitions and Atoms of Clause Structure
by: Sportiche, Dominique
Published: (1998)

Degree sequences of partite hypergraphs
by: Pasaad Kongtaln
Published: (2014)

Mitochondrial Encephalomyopathy Associated with Pyruvate Dehydrogenase Complex Deficiency: Eight Clinical Cases
by: Ekaterina A. Nikolaeva, et al.
Published: (2021)

Chapter Restricted integer partition functions
by: Alon, Noga
Published: (2014)

Flexibility in partitioning strategies of fourth graders
by: Yeliz Yazgan
Published: (2021)

Psychometric validation of the Pyruvate Kinase Deficiency Diary and Pyruvate Kinase Deficiency Impact Assessment in adults in the phase 3 ACTIVATE trial
by: David A. Andrae, et al.
Published: (2023)

Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity
by: Sujun Li, et al.
Published: (2018)

Bamboo partition / Norashikin Kamarudin ... [et al.]
by: Kamarudin, Norashikin, et al.
Published: (2016)

Host-microbe tryptophan partitioning in cardiovascular diseases
by: Matteo Antonio Russo, et al.
Published: (2023)

Cyclodextrin's Effect on Permeability and Partition of Nortriptyline Hydrochloride
by: Tatyana Volkova, et al.
Published: (2023)

Changes in myocardial lactate, pyruvate and lactate-pyruvate ratio during cardiopulmonary bypass for elective adult cardiac surgery: Early indicator of morbidity
by: P M Kapoor, et al.
Published: (2011)

Development and Application of a Dissolution-Transfer-Partitioning System (DTPS) for Biopharmaceutical Drug Characterization
by: Christian Jede, et al.
Published: (2023)

Mitapivat: New dawn in pyruvate kinase deficiency and beyond
by: Ritika Khurana, et al.
Published: (2024)

Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction
by: Isabelle Adant, et al.
Published: (2022)

South Asian Partition Fiction in English From Khushwant Singh to Amitav Ghosh
by: Rituparna, Roy
Published: (2010)

South Asian Partition Fiction in English From Khushwant Singh to Amitav Ghosh
by: Roy, Rituparna
Published: (2010)

Clique coverings and clique partitions of the K-power of graphs
by: Tanawat Wichianpaisarn
Published: (2014)

Spatial segregation and habitat partitioning of bobcat and Canada lynx
by: Robby R. Marrotte, et al.
Published: (2020)

Erythrocyte Partitioning Profile of Isosteviol in Human and Rat Blood
by: Ayorinde Adehin, PhD, et al.
Published: (2019)

Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues
by: Anusha Balla, et al.
Published: (2021)

Targeting pyruvate kinase M2 for the treatment of kidney disease
by: Dan-Qian Chen, et al.
Published: (2024)

Stem Cell Metabolism in Cancer and Healthy Tissues: Pyruvate in the Limelight
by: Cyril Corbet
Published: (2018)

Ethyl pyruvate protects against sepsis by regulating energy metabolism
by: Kang H, et al.
Published: (2016)

Disentangling Bare Nouns and Nominals Introduced by a Partitive Article
Published: (2020)

Disentangling Bare Nouns and Nominals Introduced by a Partitive Article
Published: (2020)