TXNIP inhibition in the treatment of type 2 diabetes mellitus: design, synthesis, and biological evaluation of quinazoline derivatives

Thioredoxin interacting protein (TXNIP) is a potential drug target for type 2 diabetes mellitus (T2DM) treatment. A series of quinazoline derivatives were designed, synthesised, and evaluated to inhibit TXNIP expression and protect from palmitate (PA)-induced β cell injury. In vitro cell viability a...

Full description

Saved in:
Bibliographic Details
Main Authors: Aiyun Li (Author), Li Guan (Author), Wanzhen Su (Author), Ning Zhao (Author), Xuwen Song (Author), Jin Wang (Author), Xiaoxiao Tang (Author), Weize Li (Author), Xiangying Jiao (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available