Positive feedback loop of miR-320 and CD36 regulates the hyperglycemic memory-induced diabetic diastolic cardiac dysfunction

• Main Authors: Jiabing Zhan (Author), Kunying Jin (Author), Nan Ding (Author), Yufei Zhou (Author), Guo Hu (Author), Shuai Yuan (Author), Rong Xie (Author), Zheng Wen (Author), Chen Chen (Author), Huaping Li (Author), Dao Wen Wang (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intensive glycemic control is insufficient for reducing the risk of heart failure among patients with diabetes mellitus (DM). While the "hyperglycemic memory" phenomenon is well documented, little is known about its underlying mechanisms. In this study, a type 1 DM model was established in...