Detection of Microsatellite Instability in Colorectal Cancer Patients With a Plasma-Based Real-Time PCR Analysis

• Main Authors: Namjoo Kim (Author), Sung Min Kim (Author), Beom Jae Lee (Author), Byung il Choi (Author), Hee Sook Yoon (Author), Sang Hee Kang (Author), Seung Han Kim (Author), Moon Kyung Joo (Author), Jong-Jae Park (Author), Chungyeul Kim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A microsatellite instability (MSI) test is crucial for screening for HNPCC (Hereditary nonpolyposis colorectal cancer; Lynch syndrome) and optimization of colorectal cancer (CRC) treatment. Mismatch repair (MMR) deficiency is a predictor for good response of immune checkpoint inhibitors in various m...