L-arginine, a nitric oxide precursor, reduces dapsone-induced methemoglobinemia in rats
Dapsone use is frequently associated to hematological side effects such as methemoglobinemia and hemolytic anemia, which are related to N-hydroxylation mediated by the P450 enzyme system. The aim of the present study was to evaluate the influence of L-arginine supplementation, a precursor for the sy...
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Main Authors: | Natália Valadares de Moraes (Author), Mateus Machado Bergamaschi (Author), Maria de Lourdes Pires Bianchi (Author), Juliana Bordinassi Bragheto (Author), Wilson Roberto Malfará (Author), Regina Helena Costa Queiroz (Author) |
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Format: | Book |
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Universidade de São Paulo,
2012-03-01T00:00:00Z.
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