Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus-PVPVA complex

• Main Authors: Chunliu Zhu (Author), Shuang Gong (Author), Jinsong Ding (Author), Miaorong Yu (Author), Ejaj Ahmad (Author), Yi Feng (Author), Yong Gan (Author)
• Format: Book
• Published: Elsevier, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing the degree of supersaturation of drugs and maintaining their proper stability are very important in improving the oral bioavailability of poorly soluble drugs by a supersaturated drug delivery system (SDDS). In this study, we reported a complex system of Soluplus-Copovidone (Soluplus-PVPV...