A phase II multicenter randomized study to evaluate the safety and efficacy of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World.

• Main Authors: Liliana López (Author), Braulio Valencia (Author), Fiorela Alvarez (Author), Ana Pilar Ramos (Author), Alejandro Llanos-Cuentas (Author), Juan Echevarria (Author), Iván Vélez (Author), Marina Boni (Author), Joelle Rode (Author), Juliana Quintero (Author), Alejandra Jiménez (Author), Yulied Tabares (Author), Claudia Méndez (Author), Byron Arana (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Systemic pentavalent antimonials, mainly meglumine antimoniate, continue to be the first-choice drugs for treatment of cutaneous leishmaniasis (CL) despite their toxicity, difficulty of administration and high cost. In the search for therapeutic alternatives, combining...