Multivariate generalized mixed-effects models for screening multiple adverse drug reactions in spontaneous reporting systems

Introduction: For assessing drug safety using spontaneous reporting system databases, quantitative measurements, such as proportional reporting rate (PRR) and reporting odds ratio (ROR), are widely employed to assess the relationship between a drug and a suspected adverse drug reaction (ADR). The da...

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Main Authors: Masahiko Gosho (Author), Ryota Ishii (Author), Tomohiro Ohigashi (Author), Kazushi Maruo (Author)
Format: Book
Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
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