A Case of Metastatic Extramammary Paget's Disease Responding to Trastuzumab plus Paclitaxel Combination Therapy

• Autori principali: Fumie Hanawa (Autore), Takashi Inozume (Autore), Kazutoshi Harada (Autore), Tatsuyosi Kawamura (Autore), Naotaka Shibagaki (Autore), Shinji Shimada (Autore)
• Natura: Libro
• Pubblicazione: Karger Publishers, 2011-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

There is no effective treatment for advanced extramammary Paget's disease (EMPD). The human epidermal growth factor receptor 2 (HER2) protein is often overexpressed in EMPD. Trastuzumab is a humanized monoclonal antibody against HER2 used in the treatment of breast cancers in which HER2 is over...