Leukotriene B4 loaded in microspheres regulate the expression of genes related to odontoblastic differentiation and biomineralization by dental pulp stem cells

• Main Authors: Francine Lorencetti da Silva (Author), Giuliana de Campos Chaves Lamarque (Author), Fernanda Maria Machado Pereira Cabral de Oliveira (Author), Paulo Nelson-Filho (Author), Léa Assed Bezerra da Silva (Author), Raquel Assed Bezerra Segato (Author), Lúcia Helena Faccioli (Author), Francisco Wanderley Garcia Paula-Silva (Author)
• Format: Book
• Published: BMC, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Leukotriene B4 (LTB4) is a potent lipid mediator that stimulate the immune response. Because dental pulp inflammation and dentin repair are intrinsically related responses, the aim of this research was to investigate the potential of LTB4 in inducing differentiation of dental pul...