An Improved Anticancer Drug-Response Prediction Based on an Ensemble Method Integrating Matrix Completion and Ridge Regression

• Main Authors: Chuanying Liu (Author), Dong Wei (Author), Ju Xiang (Author), Fuquan Ren (Author), Li Huang (Author), Jidong Lang (Author), Geng Tian (Author), Yushuang Li (Author), Jialiang Yang (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, we proposed an ensemble learning method, simultaneously integrating a low-rank matrix completion model and a ridge regression model to predict anticancer drug response on cancer cell lines. The model was applied to two benchmark datasets, including the Cancer Cell Line Encyclopedia (C...