Potential role of Claudin-1 immunohistochemical expression and ultrastructural changes in detecting early focal segmental glomerulosclerosis

• Main Authors: Nadia Galal Elhefnawy (Author), Nermine Mohamed Adb Raboh (Author), Ola Hassan Nada (Author), Esraa Adel Mahmoud (Author), Waleed Anwar Abd El Mohsen (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Focal segmental glomerulosclerosis (FSGS) and Minimal change disease (MCD) are two disease entities presented mainly by nephrotic syndrome. While 95% of MCD cases showed complete remission on steroid therapy, 50% of FSGS cases progress to end stage renal disease. Early sclerotic lesions...