HECT, UBA and WWE domain containing 1 represses cholesterol efflux during CD4+ T cell activation in Sjögren's syndrome

• Main Authors: Junhao Yin (Author), Jiabao Xu (Author), Changyu Chen (Author), Xinyi Ma (Author), Hanyi Zhu (Author), Lisong Xie (Author), Baoli Wang (Author), Yanxiong Shao (Author), Yijie Zhao (Author), Yu Wei (Author), Anni Hu (Author), Zhanglong Zheng (Author), Chuangqi Yu (Author), Jiayao Fu (Author), Lingyan Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by exocrine gland dysfunction, leading to loss of salivary function. Histological analysis of salivary glands from SS patients reveals a high infiltration of immune cells, particularly activated CD4+ T cells. T...