A model-based approach for a practical dosing strategy for the short, intensive treatment regimen for paediatric tuberculous meningitis

• Main Authors: Roeland E. Wasmann (Author), Tiziana Masini (Author), Kerri Viney (Author), Sabine Verkuijl (Author), Annemieke Brands (Author), Anneke C. Hesseling (Author), Helen McIlleron (Author), Paolo Denti (Author), Kelly E. Dooley (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Following infection with Mycobacterium tuberculosis, young children are at high risk of developing severe forms of tuberculosis (TB) disease, including TB meningitis (TBM), which is associated with significant morbidity and mortality. In 2022, the World Health Organization (WHO) conditionally recomm...