Prevalence of CDKN2A, CDK4, POT1, BAP1, MITF, ATM, and TERT Pathogenic Variants in a Single-Center Retrospective Series of Patients With Melanoma and Personal or Family History Suggestive of Genetic Predisposition

• Main Authors: Giada Ferrara (Author), Salvatore Paiella (Author), Giulio Settanni (Author), Melissa Frizziero (Author), Paolo Rosina (Author), Valeria Viassolo (Author)
• Format: Book
• Published: Mattioli1885, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Approximately 20%-45% of familial melanoma (FM) cases are associated with genetic predisposition. Objectives: This single-center retrospective study aimed to assess the frequency of pathogenic variants (PV) in the main melanoma-predisposing genes in patients with cutaneous melanoma and...