A mitochondrial-targeted peptide ameliorated podocyte apoptosis through a HOCl-alb-enhanced and mitochondria-dependent signalling pathway in diabetic rats and in vitro

• मुख्य लेखकों: Xiaoqiao Wang (लेखक), Dongdong Tang (लेखक), Yaowei Zou (लेखक), Xiaoyu Wu (लेखक), Yihua Chen (लेखक), Hongying Li (लेखक), Siqi Chen (लेखक), Yue Shi (लेखक), Hongxin Niu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Mitochondria play important roles in the development of diabetic kidney disease (DKD). The SS peptide is a tetrapeptide that is located and accumulated in the inner mitochondrial membrane; it reduces reactive oxygen species (ROS) and prevents mitochondrial dysfunction. Podocytes are key cellular com...