Development of dual-drug-loaded stealth nanocarriers for targeted and synergistic anti-lung cancer efficacy

• Main Authors: Juan Chen (Author), Xiaobing Yang (Author), Liuqing Huang (Author), Huixian Lai (Author), Chuanhai Gan (Author), Xuetao Luo (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Combination chemotherapy is widely exploited for suppressing drug resistance and achieving synergistic anticancer efficacy in the clinic. In this paper, the nanostructured targeting methotrexate (MTX) plus pemetrexed (PMX) chitosan nanoparticles (CNPs) were developed by modifying methoxy polye (thyl...