Induction of the intestinal membrane transporters ABCA1 and ABCG8 by 27-hydroxycholesterol through a redox mechanism

• Ngā kaituhi matua: Noemi Iaia (Author), Valerio Leoni (Author), Giuseppe Poli (Author), Fiorella Biasi (Author)
• Hōputu: Pukapuka
• I whakaputaina: Bioscientifica, 2024-08-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Objective: We tested the effect of 27-hydroxycholesterol (27OHC) on the expression and synthesis of two membrane transporters involved in sterols extrusion from the intestinal epithelium into the gut lumen: ATP-binding cassette A1 (ABCA1) and G8 (ABCG8). Special attention was given to ABCG8, a key p...