Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis

• Main Authors: Donghao Gan (Author), Wenxiang Cheng (Author), Liqing Ke (Author), Antonia RuJia Sun (Author), Qingyun Jia (Author), Jianhai Chen (Author), Jietao Lin (Author), Jian Li (Author), Zhanwang Xu (Author), Peng Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical studies have shown that pirfenidone (PFD) effectively relieves joint pain in rheumatoid arthritis (RA) patients. However, the detailed mechanisms underlying the anti-RA effects of PFD have not been investigated. This study was undertaken to investigate the repurposing of PFD for the treatme...